The role played by alternative splicing in antigenic variability in
Por um escritor misterioso
Last updated 29 março 2025

Endo-parasites that affect humans include Plasmodium, the causative agent of malaria, which remains one of the leading causes of death in human beings. Despite decades of research, vaccines to this and other endo-parasites remain elusive. This is in part due to the hyper-variability of the parasites surface proteins. Generally these surface proteins are encoded by a large family of genes, with only one being dominantly expressed at certain life stages. Another layer of complexity can be introduced through the alternative splicing of these surface proteins. The resulting isoforms may differ from each other with regard to cell localisation, substrate affinities and functions. They may even differ in structure to the extent that they are no longer recognised by the host’s immune system. In many cases this leads to changes in the N terminus of these proteins. The geographical localisation of endo-parasitic infections around the tropics and the highest incidences of HIV-1 infection in the same areas, adds a further layer of complexity as parasitic infections affect the host immune system resulting in higher HIV infection rates, faster disease progression, and an increase in the severity of infections and complications in HIV diagnosis. This review discusses some examples of parasite surface proteins that are alternatively spliced in trypanosomes, Plasmodium and the parasitic worm Schistosoma as well as what role alternate splicing may play in the interaction between HIV and these endo-parasites.

PDF) The role played by alternative splicing in antigenic

Immunoglobulin class switching - Wikipedia

PDF) The role played by alternative splicing in antigenic

Mechanistic Similarities between Antigenic Variation and Antibody

The relevance of alternative RNA splicing to pharmacogenomics

The role of alternative splicing in adaptation and evolution
Targeting the RNA G-Quadruplex and Protein Interactome for

Types of viral and mammalian alternative RNA splicing. Examples of

10/26/17 B-cell diversity [cont.] Flashcards

Telomere and Subtelomere R-loops and Antigenic Variation in

The role played by alternative splicing in antigenic variability

Transcriptome analysis of alternative splicing in the pathogen
Recomendado para você
-
Scp 7148 Techno Heart by DrJackBrightNeko on DeviantArt29 março 2025
-
SCP-5812 Ghostyard Safe [SCP Document Reading]29 março 2025
-
Scp - 40- z The ditto29 março 2025
-
Whipple 6 Rib Supercharger Pulley (2014+ GM DI LT1) SCP-6-GMT29 março 2025
-
Version 23.11.0 introduces error fatal: could not read Username29 março 2025
-
30.59% OFF on B2S ANITECH เครื่องบดสับอเนกประสงค์ รุ่น SCP300 สีดำ29 março 2025
-
Customer Segmentation Analysis - Emirates29 março 2025
-
PDF] Prevalence of gastrointestinal disorders in individuals with
RASopathies : MayRAS /MAP /ERK pathway dysfunctions be a model of neuropathic pain and visceral hypersensitivity? by Chiara Leoni29 março 2025 -
my avatar is a skulldog not an scp. its so annoying #robloxtiktok #rob29 março 2025
-
Digipartspower AC/DC Adapter for MS MelodySusie 7129 março 2025
você pode gostar
-
Download AI Art Generator - Fantasy APK29 março 2025
-
Luton promoted to Premier League after playoff win over Coventry29 março 2025
-
eu sei que você pensou em alguém. Marca ou envia pra essa pessoa #humo29 março 2025
-
FRC Chair Jan du Plessis Blames London's Decline on 'Narrow British Way of Life' - Bloomberg29 março 2025
-
Real Love Test - Love Tester - APK Download for Android29 março 2025
-
LEGO Rainbow Friends Sets, Unofficial LEGO minifigures29 março 2025
-
Green solvents for drug synthesis - ScienceDirect29 março 2025
-
Roblox HD wallpaper-4K Background APK (Android App) - Free Download29 março 2025
-
ishowspeed - Roblox29 março 2025
-
Google vai acabar com Chrome Apps no Windows, macOS e Linux29 março 2025