The role played by alternative splicing in antigenic variability in
Por um escritor misterioso
Last updated 30 maio 2024
Endo-parasites that affect humans include Plasmodium, the causative agent of malaria, which remains one of the leading causes of death in human beings. Despite decades of research, vaccines to this and other endo-parasites remain elusive. This is in part due to the hyper-variability of the parasites surface proteins. Generally these surface proteins are encoded by a large family of genes, with only one being dominantly expressed at certain life stages. Another layer of complexity can be introduced through the alternative splicing of these surface proteins. The resulting isoforms may differ from each other with regard to cell localisation, substrate affinities and functions. They may even differ in structure to the extent that they are no longer recognised by the host’s immune system. In many cases this leads to changes in the N terminus of these proteins. The geographical localisation of endo-parasitic infections around the tropics and the highest incidences of HIV-1 infection in the same areas, adds a further layer of complexity as parasitic infections affect the host immune system resulting in higher HIV infection rates, faster disease progression, and an increase in the severity of infections and complications in HIV diagnosis. This review discusses some examples of parasite surface proteins that are alternatively spliced in trypanosomes, Plasmodium and the parasitic worm Schistosoma as well as what role alternate splicing may play in the interaction between HIV and these endo-parasites.
PDF) The role played by alternative splicing in antigenic
Immunoglobulin class switching - Wikipedia
PDF) The role played by alternative splicing in antigenic
Mechanistic Similarities between Antigenic Variation and Antibody
The relevance of alternative RNA splicing to pharmacogenomics
The role of alternative splicing in adaptation and evolution
Targeting the RNA G-Quadruplex and Protein Interactome for
Types of viral and mammalian alternative RNA splicing. Examples of
10/26/17 B-cell diversity [cont.] Flashcards
Telomere and Subtelomere R-loops and Antigenic Variation in
The role played by alternative splicing in antigenic variability
Transcriptome analysis of alternative splicing in the pathogen
Recomendado para você
-
Pair of Swan Candlesticks by Matthew Hilton, England, 198030 maio 2024
-
Scp 7148 Techno Heart by DrJackBrightNeko on DeviantArt30 maio 2024
-
SCP-5812 Ghostyard Safe [SCP Document Reading]30 maio 2024
-
SCP-7149 - SCP Foundation30 maio 2024
-
The Rare Breed 1995 Vintage VHS Tape Vcr Classic Video James30 maio 2024
-
Plants, Free Full-Text30 maio 2024
-
Acessórios para Ferramentas30 maio 2024
-
Digipartspower AC/DC Adapter for MS MelodySusie 7130 maio 2024
-
UpBright 30V AC/DC Adapter Compatible with XBlue30 maio 2024
-
The role played by alternative splicing in antigenic variability30 maio 2024
você pode gostar
-
New Game Roblox Double Layer Flip Pen Bag Polyester for Primary and Secondary School Students Stationery Box Christmas Gift Toy30 maio 2024
-
SPARTA - SERVIÇOS30 maio 2024
-
Ytshorts:Sad Cat Dance (Rainbow Friends Meme) Part FINAL Ft.Red🦊#ytsh30 maio 2024
-
SlendyTubbies 3 : Android Multiplayer!30 maio 2024
-
Atleta recebe apoio da Seel para disputar Campeonato Paraense de30 maio 2024
-
Tik Tok — MC Divertida Maria Clara30 maio 2024
-
What Is the Curse Mark on Sasuke in 'Naruto'? Origin and Meaning, Explained30 maio 2024
-
Stickman Meme Battle Simulator相似游戏下载预约_豌豆荚30 maio 2024
-
TOP 10 BEST Tim Hortons in Montreal, QC - December 2023 - Yelp30 maio 2024
-
80+ Rockstar Games Stock Videos and Royalty-Free Footage - iStock30 maio 2024