Genes that Escape Silencing on the Second X Chromosome May Drive Disease

When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease: Cell

Contiguous erosion of the inactive X in human pluripotency concludes with global DNA hypomethylation - ScienceDirect

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations

Escape from X chromosome inactivation and female bias of autoimmune diseases, Molecular Medicine

Escape Artists of the X Chromosome: Trends in Genetics

IJMS, Free Full-Text

Epigenomes, Free Full-Text

How do genes that escape from X‐chromosome inactivation contribute to Turner syndrome? - Peeters - 2019 - American Journal of Medical Genetics Part C: Seminars in Medical Genetics - Wiley Online Library

The human inactive X chromosome modulates expression of the active X chromosome - ScienceDirect

Epigenomes, Free Full-Text

Escaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases - ScienceDirect

Chromosome Xp - an overview