PDF] Physiological and molecular basis of extreme radioresistance

The most recent advances in understanding on different aspects of D. radiodurans that are shown to be important for its extraordinary radioresistance are reviewed. Deinococcus radiodurans is characterized for its extraordinary radioresistance. An efficient DNA strandbreak repair and strong oxidative stress tolerance are amongst the mechanisms that contribute to its extreme phenotypes. The multipartite genome structure, recombination repair without RecBC enzymes, absence of SOS response and the roles of serine/ threonine protein kinase in DNA damage response, and the small molecules protecting proteins from oxidative damage are some of the other unique features of this bacterium. Here, we review the most recent advances in our understanding on different aspects of D. radiodurans that are shown to be important for its extraordinary radioresistance.

PDF) Radioresistance of Deinococcus radiodurans: Functions necessary to survive ionizing radiation are also necessary to survive prolonged desiccation

Cancers, Free Full-Text

Correlation of hypoxia PET tracer uptake with hypoxic radioresistance in cancer cells: PET biomarkers of resistance to stereotactic radiation therapy? - ScienceDirect

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PDF) Physiological and molecular basis of extreme radioresistance in Deinococcus radiodurans

ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer, Journal of Experimental & Clinical Cancer Research

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The radioresistant and survival mechanisms of Deinococcus radiodurans

Molecular Radiation Biology

PDF] Physiological and molecular basis of extreme radioresistance in Deinococcus radiodurans

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