Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV

Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV

Clustering of oral mycobiome samples. (A) A dendrogram showing

HIV affects polyamine metabolism and T cell lineages

Antiviral factors and type I/III interferon expression associated with regulatory factors in the oral epithelial cells from HIV-1-serodiscordant couples

Frontiers The initial interplay between HIV and mucosal innate immunity

PDF] Regulating T cell differentiation through the polyamine spermidine.

Exogenous polyamines do not rescue metabolism in 25HC treated NK cells.

HIV and Aging: HIV seen as a Chronic Inflammatory Intestinal Disease.

Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy, Journal of Hematology & Oncology

PDF) Metabolome and transcriptome analysis of oral mucosa of HIV+ patients reveal a role for polyamine metabolic pathway in T cell dysfunction

Oral immune dysfunction is associated with the expansion of FOXP3+PD-1+Amphiregulin+ T cells during HIV infection

Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV

Frontiers The altered metabolites contributed by dysbiosis of gut microbiota are associated with microbial translocation and immune activation during HIV infection