The diversity and commonalities of the radiation-resistance

Deinococcus is an extremophilic microorganism found in a wide range of habitats, including hot springs, radiation-contaminated areas, Antarctic soils, deserts, etc., and shows some of the highest levels of resistance to ionizing radiation known in nature. The highly efficient radiation-protection mechanisms of Deinococcus depend on a combination of passive and active defense mechanisms, including self-repair of DNA damage (homologous recombination, MMR, ER and ESDSA), efficient cellular damage clearance mechanisms (hydrolysis of damaged proteins, overexpression of repair proteins, etc.), and effective clearance of reactive oxygen species (ROS). Due to these mechanisms, Deinococcus cells are highly resistant to oxidation, radiation and desiccation, which makes them potential chassis cells for wide applications in many fields. This article summarizes the latest research on the radiation-resistance mechanisms of Deinococcus and prospects its biotechnological application potentials.

A new perspective on radiation resistance based on Deinococcus radiodurans

Frontiers Differences in the Establishment of Gut Microbiota and Metabolome Characteristics Between Balb/c and C57BL/6J Mice After Proton Irradiation

The Ecology of Nonecological Speciation and Nonadaptive Radiations: Trends in Ecology & Evolution

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Extensive Diversity of Ionizing-Radiation-Resistant Bacteria Recovered from Sonoran Desert Soil and Description of Nine New Species of the Genus Deinococcus Obtained from a Single Soil Sample

The radioresistant and survival mechanisms of Deinococcus radiodurans - ScienceDirect

A new era of radiation resistance bacteria in bioremediation and production of bioactive compounds with therapeutic potential and other aspects: An in-perspective review - ScienceDirect

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Radiation-resistant extremophiles and their potential in biotechnology and therapeutics

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Efficient Removal of [UO2]2+, Cs+, and Sr2+ Ions by Radiation-Resistant Gallium Thioantimonates

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Adjusting the lens of invasion biology to focus on the impacts of climate-driven range shifts

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