Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.

The pathogenesis of Niemann–Pick type C disease: a role for

A proposed model for the pathogenesis of Niemann-Pick disease type

Niemann–Pick type C disease: cellular pathology and

PDF] Efficient Investigation and Differential Diagnosis of

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Niemann–Pick type C disease: cellular pathology and

Our research - Ruđer Bošković Institute

Marko KOSICEK, PhD, Ruđer Bošković Institute, Zagreb

Solving neurodegeneration: common mechanisms and strategies for