A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
Por um escritor misterioso
Last updated 18 abril 2025

Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…

Designed to kill: novel menin-MLL inhibitors target MLL-rearranged

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors

ZMYND8-regulated IRF8 transcription axis is an acute myeloid

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors

Pharmacologic Inhibition of the Menin-MLL Interaction Blocks

PDF) Development of an orally bioavailable selective inhibitor of
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