How does SARS-CoV-2 evade the immune defences?

As most of pathogens, SARS-CoV-2 can be recognized by pattern recognition receptors on innate. Normally, this recognition helps the innate immunity to eliminate the infection or to activate the adaptive immune responses, however, SARS-CoV-2 can use its proteins such as M, N, NSP1 and PLpro to interfere with these pathways.

Frontiers Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past

Frontiers Uncovering Novel Viral Innate Immune Evasion Strategies: What Has SARS-CoV-2 Taught Us?

Frontiers SARS-CoV-2 Variants, Vaccines, and Host Immunity

Why Viruses Like SARS-CoV-2 Can Reinfect Us, Evade Immune Response

Cell-mediated immunity to SARS-CoV-2

SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients

Innate immune sensing of coronavirus and viral evasion strategies

SARS-CoV-2 learned the 'Alpha'bet of immune evasion

Viruses Evade the Immune Response Video Tutorial & Practice