Expansive and Diverse Phenotypic Landscape of Field Aedes aegypti (Diptera: Culicidae) Larvae with Differential Susceptibility to Temephos: Beyond Metabolic Detoxification
Por um escritor misterioso
Last updated 31 março 2025

Arboviruses including dengue, Zika, and chikungunya are amongst the most significant public health concerns worldwide. Arbovirus control relies on the use of insecticides to control the vector mosquito Aedes aegypti (Linnaeus), the success of which is threatened by widespread insecticide resistance. The work presented here profiled the gene expression of Ae. aegypti larvae from field populations of Ae. aegypti with differential susceptibility to temephos originating from two Colombian urban locations, Bello and Cúcuta, previously reported to have distinctive disease incidence, socioeconomics, and climate. We demonstrated that an exclusive field-to-lab (Ae. aegypti strain New Orleans) comparison generates an over estimation of differential gene expression (DGE) and that the inclusion of a geographically relevant field control yields a more discrete, and likely, more specific set of genes. The composition of the obtained DGE profiles is varied, with commonly reported resistance associated genes including detoxifying enzymes having only a small representation. We identify cuticle biosynthesis, ion exchange homeostasis, an extensive number of long noncoding RNAs, and chromatin modelling among the differentially expressed genes in field resistant Ae. aegypti larvae. It was also shown that temephos resistant larvae undertake further gene expression responses when temporarily exposed to temephos. The results from the sampling triangulation approach here contribute a discrete DGE profiling with reduced noise that permitted the observation of a greater gene diversity, increasing the number of potential targets for the control of insecticide resistant mosquitoes and widening our knowledge base on the complex phenotypic network of the Ae. aegypti response to insecticides.

AdoR regulated the Hsp70 protein level and influenced the stress

Susceptibility of Ae. aegypti larvae from Thailand to temephos and

Resistance to the larvicide temephos and altered egg and larval

Parent-Child association for functionally enriched Gene Ontology

Genomic amplification associated with carboxylesterase over

PDF] Detection of Ace-1 gene with insecticides resistance in Aedes

Genes, Free Full-Text

RNA-Seq Comparison of Larval and Adult Malpighian Tubules of the

One does not simply apply larvicides: Aedes aegypti from

Summary of the genes differentially transcribed in the comparisons

PDF] The efficacy of a chitin synthesis inhibitor against field

Association between selected P450 gene SNP frequency and

Mod(mdg4) as a downstream target of ENT2/AdoR pathway modulated
Recomendado para você
-
PDF) A functional vulnerability framework for biodiversity conservation31 março 2025
-
Comment Thomas Courbe réorganise la DGE à Bercy - 18/11/2019 - LA LETTRE31 março 2025
-
Viruses Announcements31 março 2025
-
PDF) A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti : From genomic characterization to high‐throughput field detection31 março 2025
-
Genes, Free Full-Text31 março 2025
-
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers, Breast Cancer Research31 março 2025
-
Aloise sauvage hi-res stock photography and images - Page 3 - Alamy31 março 2025
-
explore globally engage locally - Smithsonian Institution31 março 2025
-
vocab.txt · Geotrend/distilbert-base-en-pl-cased at 8d3f09ab0371534b7b7fd7e5ffb6998049ddd79231 março 2025
-
Feliciana sentinel. [volume] (St. Francisville, La.) 1877-1892, December 01, 1877, Image 1 « Chronicling America « Library of Congress31 março 2025
você pode gostar
-
Call of Duty®: Modern Warfare® - Call of Duty: MW31 março 2025
-
Watch Over 20 Minutes Of New Final Fantasy XVI Gameplay - Game Informer31 março 2025
-
Leadale No Daichi Nite Chua Tek Ming~*Anime Power*~ !LiVe FoR AnImE, aNiMe FoR LiFe!31 março 2025
-
Dedra Meero, Villains Wiki31 março 2025
-
Seasons 1-9 of 'Naruto' Leaving Netflix in November 2022 - What's on Netflix31 março 2025
-
Legend of Legendary Heroes 1 and 2 – more than what it looks - Anime Diet31 março 2025
-
Psst… Its Screech - Roblox Doors - Roblox - Kids T-Shirt31 março 2025
-
Jogo Uno - Minimalista - Mattel Original Lacrado | Cacareco Mattel Nunca Usado 85818135 | enjoei31 março 2025
-
Crítica do Stumble Guys: Um clássico jogo de ação nocaute31 março 2025
-
Lasserre Comanche II-A .38 SPL Revolver31 março 2025