Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
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Last updated 19 abril 2025


One-Pot 1,1-Dihydrofluoroalkylation of Amines Using Sulfuryl Fluoride

Advances in targeting Phosphodiesterase 1: From mechanisms to potential therapeutics - ScienceDirect

Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists

Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. - Abstract - Europe PMC

Development of fluorescent peptide G protein‐coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators - Farmer - 2022 - The FASEB Journal - Wiley Online Library

Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists

CXCR2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis - ScienceDirect

Discovery of CVN417, a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction

Directing the Metabolism of Drugs Away from CYP450: The Use of Oxetane Rings

Discovery, structure-activity relationship study and biological evaluation of 2-thioureidothiophene-3-carboxylates as a novel class of C-X-C chemokine receptor 2 (CXCR2) antagonists - ScienceDirect

WO2014033122A1 - Inhibitors of cd40-traf6 interaction - Google Patents

Development of fluorescent peptide G protein‐coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators - Farmer - 2022 - The FASEB Journal - Wiley Online Library
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