Cells, Free Full-Text
Por um escritor misterioso
Last updated 19 março 2025

The primary cilium has gone from being a vestigial organelle to a crucial signaling hub of growing interest given the association between a group of human disorders, collectively known as ciliopathies, and defects in its structure or function. In recent years many ciliogenesis proteins have been observed at extraciliary sites in cells and likely perform cilium-independent functions ranging from regulation of the cytoskeleton to vesicular trafficking. Perhaps the most striking example is the non-ciliated T lymphocyte, in which components of the ciliary machinery are repurposed for the assembly and function of the immunological synapse even in the absence of a primary cilium. Furthermore, the specialization traits described at the immunological synapse are similar to those seen in the primary cilium. Here, we review common regulators and features shared by the immunological synapse and the primary cilium that document the remarkable homology between these structures.

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Cancers, Free Full-Text

Cell-free methods to produce structurally intact mammalian membrane proteins

STEM CELLS: Vol 35, No 5

Cell-free mutant analysis combined with structure prediction of a lasso peptide biosynthetic protein B2

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Cells, Free Full-Text
Labile coat: reason for noninfectious cell-free varicella-zoster virus in culture. - Abstract - Europe PMC

An illustration of the full-duplex cell-free massive MIMO system.

Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells, Gut Pathogens
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