Cells, Free Full-Text
Por um escritor misterioso
Last updated 26 junho 2024
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Silk has a long history as an exclusive textile, but also as a suture thread in medicine; nowadays, diverse cell carriers are manufactured from silk. Its advantages are manifold, including high biocompatibility, biomechanical strength and processability (approved for nearly all manufacturing techniques). Silk’s limitations, such as scarcity and batch to batch variations, are overcome by gene technology, which allows for the upscaled production of recombinant “designed” silk proteins. For processing thin fibroin filaments, the sericin component is generally removed (degumming). In contrast to many synthetic biomaterials, fibroin allows for superior cell adherence and growth. In addition, silk grafts demonstrate superior mechanical performance and long-term stability, making them attractive for anterior cruciate ligament (ACL) tissue engineering. Looking at these promising properties, this review focusses on the responses of cell types to silk variants, as well as their biomechanical properties, which are relevant for ACL tissue engineering. Meanwhile, sericin has also attracted increasing interest and has been proposed as a bioactive biomaterial with antimicrobial properties. But so far, fibroin was exclusively used for experimental ACL tissue engineering approaches, and fibroin from spider silk also seems not to have been applied. To improve the bone integration of ACL grafts, silk scaffolds with osteogenic functionalization, silk-based tunnel fillers and interference screws have been developed. Nevertheless, signaling pathways stimulated by silk components remain barely elucidated, but need to be considered during the development of optimized silk cell carriers for ACL tissue engineering.
JTurkGerGynecolAssoc on X: Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study You can see the free full text of
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Advances and applications of cell-free systems for metabolic production - ScienceDirect
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PDF) Comparative separation methods and biological characteristics of human placental and umbilical cord mesenchymal stem cells in serum-free culture conditions
Nature Reviews Molecular Cell Biology on X: From May cover Challenges and directions in studying cell–cell communication by #ExtracellularVesicles @DaveCarter1234 @guillaume_niel @VaderPieter Clayton Lambert & Raposo #EVsAreCool FREE pdf: https
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Cell-Free DNA and Apoptosis: How Dead Cells Inform About the Living - ScienceDirect
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Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer
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IJMS, Free Full-Text
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Cells, Free Full-Text
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The cell-free system: A new apparatus for affordable, sensitive, and portable healthcare - ScienceDirect
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Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system, Inflammation and Regeneration
Mol Imaging Radionucl Ther on X: The Role of a Bone SPECT/CT Scan in the Follow-up of a Solitary Bone Lesion in a Patient with Langerhans' Cell Histiocytosis You can see the
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Experimental design of upsidedown, upside-up, and cell-free control
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Cells, Free Full-Text
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The emerging impact of cell-free chemical biosynthesis - ScienceDirect
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Sequencing of Circulating Cell-free DNA during Pregnancy
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