Cancers, Free Full-Text
Por um escritor misterioso
Last updated 19 março 2025

Ubiquitin-like, containing PHD and RING finger domain, (UHRF) family members are overexpressed putative oncogenes in several cancer types. We evaluated the protein abundance of UHRF family members in acute leukemia. A marked overexpression of UHRF1 protein was observed in ALL compared with AML. An analysis of human leukemia transcriptomic datasets revealed concordant overexpression of UHRF1 in B-Cell and T-Cell ALL compared with CLL, AML, and CML. In-vitro studies demonstrated reduced cell viability with siRNA-mediated knockdown of UHRF1 in both B-ALL and T-ALL, associated with reduced c-Myc protein expression. Mechanistic studies indicated that UHRF1 directly interacts with c-Myc, enabling ALL expansion via the CDK4/6-phosphoRb axis. Our findings highlight a previously unknown role of UHRF1 in regulating c-Myc protein expression and implicate UHRF1 as a potential therapeutic target in ALL.

Cancer Anniversary

Know the signs of cancer to catch it early

PDF) Treatment outcome with low-dose-rate interstitial

cancer free Poster for Sale by NiceShirtY
Flow Cytometric Analysis Of Several Cancer Cell Lines Breast

Cancer-Free Creations

O Amar Mota Bou Get File - Colaboratory

Free PSD Breast cancer awareness editable text effect
.jpg)
Thoracic Cancer - Wiley Online Library
Blood Test for Cancer Screening

Rare Cancer Day - National Organization for Rare Disorders

Mortality from leading cancers in districts of England from 2002
Detection of HPV-16 DNA by PCR in histologically cancer free lymph
Blood Test for Cancer Screening

PDF) Combination of tumor markers predicts progression and
Recomendado para você
-
NEON FEAR19 março 2025
-
PD-L1 upregulation by lytic induction of Epstein-Barr Virus - ScienceDirect19 março 2025
-
PreciControl CMV IgG - 04784600190 - Bioprom19 março 2025
-
Bright Eyes Pets Breeze The Green Owl Neon Plush Toy Interactive19 março 2025
-
Blue and white manga cover Photographic Print by mia-igg19 março 2025
-
Stencil Fundo Tijolinho Irregular - 20x15cm - Ref. 16619 março 2025
-
A Girl with a Bright Red Manicure Holds a Coronavirus Test and a Lancet for a Blood Test in Her Hand. Determination of IgG and IgM Stock Photo - Image of girl19 março 2025
-
Predominant Nuclear Localization of Mammalian Target of Rapamycin in Normal and Malignant Cells in Culture - ScienceDirect19 março 2025
-
IL-3 is a novel target to interfere with tumor vasculature19 março 2025
-
Shop UGG Australia ZUMA Unisex Neon Color Kids Girl Sandals by angelforest19 março 2025
você pode gostar
-
Nova expansão gratuita para o Metin2 - Gaming Portugal19 março 2025
-
BLOX FRUITS Script Mobile UPDATE 20 AUTO FARM NEW AREA, SMOOTH19 março 2025
-
The Hidden Treasure of Area Zero Part 1: The Teal Mask DLC para19 março 2025
-
God of War III Remastered - PlayStation 4, PlayStation 419 março 2025
-
Trading Badge - Saikyou Onmyouji no Isekai Tenseiki (【BOX】最強19 março 2025
-
future dairy mirai nikki gif19 março 2025
-
O prodígio português de 16 anos que quer ser Grande Mestre de xadrez aos 18 – Observador19 março 2025
-
Dragon Ball - Vol 1 - kanzenban Edition - ISBN:978408873444619 março 2025
-
Y (Alphabet Lore) - Fandom of Halloween Specials Archive19 março 2025
-
greenscreen Overlord Season 2 #overlord #anime19 março 2025